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Keywords recombinant hirudin;Pichia pastoris;glycerol; 关键词重组水蛭素;毕赤酵母;甘油;
Keywords Recombinant hirudin;Expression;Purification;Assay; 重组水蛭素;表达;纯化;活性检测;
Keywords Recombinant hirudin;Selenite cataract;Galactose cataract;Pirenoxine;Irritation; 重组水蛭素;硒性白内障;糖性白内障;白内停;刺激性;
Keywords recombinant hirudin;fibrin;thrombin-activatable fibrinolysis inhibitor;factor XIII; 重组水蛭素;纤维蛋白;凝血酶激活的纤溶抑制物;XIII因子;
Keywords recombinant hirudin;xenopus pulmonary membrane;transport;mechanism;pulmonary absorption; 重组水蛭素;蟾蜍肺泡膜;转运;机制;肺部吸收;
Keywords recombinant hirudin（rH）;disseminated intravascular coagulation（DIC）;pharmacological studies; 重组水蛭素;弥散性血管内凝血;药效学;
Keywords Recombinant hirudin;Capacitive immunosensors;Thioctic acid （TA）;Mercaptoacetic acid （MAA）;Self-assembled monolayers （SAMs）;Regeneration; 关键词重组水蛭素;电容型免疫传感器;巯辛酸;巯基乙酸;自组装单层膜;再生;
Keywords Recombination hirudin;Quanlity control;Plasmid;C terminal sequence;Residual tissue DNA;Tropina; 重组水蛭素;质量控制;质粒;C端序列;残留DNA;菌体蛋白;
Keywords recombination hirudin;nasal epithelium toxity;absorption enhancers;ciliary movement;adhensive materials;nasal spary; 重组水蛭素;鼻黏膜毒性;吸收促进剂;纤毛运动;生物黏附材料;鼻腔喷雾剂;
As a direct thrombin inhibitor, recombinant hirudin(r-hirudin) has played an important role in clinical use. 作为直接凝血酶抑制剂,重组水蛭素在临床上的应用已越来越重要。
AIM:To evaluate the effect of recombinant hirudin (r-hirudin) in reducing neointimal proliferation after balloon angioplasty in rabbits. 目的：探讨重组水蛭素对兔髂总动脉球囊损伤后内膜增殖的影响。
Greinachea A, lubenow N. Recombinant hirudin in clinical practice: focus on lepirudin[J]. Circulation, 2001,103 (10) :1479. 黄震华.;新型抗和抗血小板新药-重组水蛭素[J]
The activity of hirudin was determined. RESULTS The activity of recombinant hirudin derivation in the culture medium reached 10 ATU/ml and a certain inhibitory effect on platelet condensation was also observed. 结果：细胞培液中，重组水蛭素衍生物的活性达到10ATU/ml，并有抗血小板凝集作用。
Absorption of recombinant hirudin in rats GI tract 重组水蛭素在大鼠胃肠道中的吸收
Keywords recombinant;immunotoxin;fusion protein; 重组;免疫毒素;融合蛋白;
Transport of recombinant hirudin across xenopus pulmonary membrane 重组水蛭素经蟾蜍肺泡膜的转运研究
Keywords recombinant proteins;hirudin;pharmacokinetics;enzyme-linked immunosorbent assay;partial thromboplastin time; 重组蛋白质类;水蛭素;药物动力学;酶联免疫吸附测定;部分促凝血酶原时间;
Keywords hirudin;recombinant hirudin;biological half-life;anticoagulant activity;activated partial thromboplastin time（APTT）; 水蛭素;重组水蛭素;生物半衰期;抗凝活性;APTT;
Prevention and Treatment of Recombinant Hirudin on Rats'Galatose Cataract 重组水蛭素对大鼠半乳糖性白内障的防治作用
Keywords recombinant BCG;freeze drying;plasmid;storage;stability; 重组卡介苗;冷冻干燥;质粒;保存;稳定性;